PI3Kalpha-IN-14, CAS [[3026856-46-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-157125
Hersteller Artikelnummer:
HY-157125
Alternativnummer:
MCE-HY-157125-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
PI3Kalpha-IN-14 (compound F8) is a selective PI3Kalpha inhibitor with an IC50 of 0.14 nM. PI3Kalpha-IN-14 induces a great decrease in mitochondrial membrane which caused cell cycle arrest at G1 phase and apoptosis in U87-MG cells. PI3Kalpha-IN-14 shows significant anti-proliferative activities against three tumor-derived cell lines (PC-3: IC50 of 0.28 µM, HCT-116: IC50 of 0.57 µM, and U87-MG: IC50 of 1.37 µM)[1].
Molekulargewicht:
643.04
CAS Nummer:
[3026856-46-9]
Formel:
C28H29ClF2N10O4
Target-Kategorie:
Apoptosis,PI3K
Anwendungsbeschreibung:
MCE Product type: Reference compound
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