PI3Kalpha-IN-14, CAS [[3026856-46-9]] Preis auf Anfrage

Artikelnummer: MCE-HY-157125
Artikelname: PI3Kalpha-IN-14, CAS [[3026856-46-9]] Preis auf Anfrage
Artikelnummer: MCE-HY-157125
Hersteller Artikelnummer: HY-157125
Alternativnummer: MCE-HY-157125-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
PI3Kalpha-IN-14 (compound F8) is a selective PI3Kalpha inhibitor with an IC50 of 0.14 nM. PI3Kalpha-IN-14 induces a great decrease in mitochondrial membrane which caused cell cycle arrest at G1 phase and apoptosis in U87-MG cells. PI3Kalpha-IN-14 shows significant anti-proliferative activities against three tumor-derived cell lines (PC-3: IC50 of 0.28 µM, HCT-116: IC50 of 0.57 µM, and U87-MG: IC50 of 1.37 µM)[1].
Molekulargewicht: 643.04
CAS Nummer: [3026856-46-9]
Formel: C28H29ClF2N10O4
Target-Kategorie: Apoptosis,PI3K
Anwendungsbeschreibung: MCE Product type: Reference compound