PI3Kalpha-IN-14, CAS [[3026856-46-9]] Preis auf Anfrage

Product Overview

• Article Name: PI3Kalpha-IN-14, CAS [[3026856-46-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-157125
• Supplier Catalog Number: HY-157125
• Alternative Catalog Number: MCE-HY-157125-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PI3Kalpha-IN-14 (compound F8) is a selective PI3Kalpha inhibitor with an IC50 of 0.14 nM. PI3Kalpha-IN-14 induces a great decrease in mitochondrial membrane which caused cell cycle arrest at G1 phase and apoptosis in U87-MG cells. PI3Kalpha-IN-14 shows significant anti-proliferative activities against three tumor-derived cell lines (PC-3: IC50 of 0.28 µM, HCT-116: IC50 of 0.57 µM, and U87-MG: IC50 of 1.37 µM)[1].

Product Properties

• Molecular Weight: 643.04
• CAS Number: [3026856-46-9]
• Formula: C28H29ClF2N10O4
• Target: Apoptosis,PI3K

Application Notes

• Application Notes: MCE Product type: Reference compound