Vercirnon, CAS [[698394-73-9]]

Artikelnummer: MCE-HY-15724
Artikelname: Vercirnon, CAS [[698394-73-9]]
Artikelnummer: MCE-HY-15724
Hersteller Artikelnummer: HY-15724
Alternativnummer: MCE-HY-15724-100MG,MCE-HY-15724-25MG,MCE-HY-15724-10MG,MCE-HY-15724-50MG,MCE-HY-15724-5MG,MCE-HY-15724-10MMX1ML
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: GSK-1605786, CCX282-B, Traficet-EN
Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1].
Molekulargewicht: 444.93
Reinheit: 98.01
CAS Nummer: [698394-73-9]
Formel: C22H21ClN2O4S
Target-Kategorie: CCR
Anwendungsbeschreibung: MCE Product type: Reference compound