Vercirnon, CAS [[698394-73-9]]

Product Overview

• Article Name: Vercirnon, CAS [[698394-73-9]]
• Biozol Catalog Number: MCE-HY-15724
• Supplier Catalog Number: HY-15724
• Alternative Catalog Number: MCE-HY-15724-25MG,MCE-HY-15724-10MMX1ML,MCE-HY-15724-10MG,MCE-HY-15724-5MG,MCE-HY-15724-50MG,MCE-HY-15724-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: GSK-1605786, CCX282-B, Traficet-EN

Product Description

Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1].

Product Properties

• Molecular Weight: 444.93
• Purity: 98.01
• CAS Number: [698394-73-9]
• Formula: C22H21ClN2O4S
• Target: CCR

Application Notes

• Application Notes: MCE Product type: Reference compound1