MS39, CAS [[2675490-92-1]]

Artikelnummer: MCE-HY-157581
Artikelname: MS39, CAS [[2675490-92-1]]
Artikelnummer: MCE-HY-157581
Hersteller Artikelnummer: HY-157581
Alternativnummer: MCE-HY-157581-50MG,MCE-HY-157581-10MG,MCE-HY-157581-5MG,MCE-HY-157581-100MG,MCE-HY-157581-1MG,MCE-HY-157581-25MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells[1].
Molekulargewicht: 1056.72
Reinheit: 99.89
CAS Nummer: [2675490-92-1]
Formel: C55H71ClFN9O7S
Target-Kategorie: EGFR,PROTACs
Anwendungsbeschreibung: MCE Product type: Reference compound