MS39, CAS [[2675490-92-1]]

Product Overview

• Article Name: MS39, CAS [[2675490-92-1]]
• Biozol Catalog Number: MCE-HY-157581
• Supplier Catalog Number: HY-157581
• Alternative Catalog Number: MCE-HY-157581-1MG,MCE-HY-157581-100MG,MCE-HY-157581-50MG,MCE-HY-157581-25MG,MCE-HY-157581-10MG,MCE-HY-157581-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells[1].

Product Properties

• Molecular Weight: 1056.72
• Purity: 99.89
• CAS Number: [2675490-92-1]
• Formula: C55H71ClFN9O7S
• Target: EGFR,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound1