Tirabrutinib (ONO-4059) is an orally active Brutons Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies[1][2][3][4].
Molekulargewicht:
454.48
Reinheit:
99.71
CAS Nummer:
[1351636-18-4]
Formel:
C25H22N6O3
Target-Kategorie:
Apoptosis,Btk
Anwendungsbeschreibung:
MCE Product type: Reference compound
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