Tirabrutinib (ONO-4059) is an orally active Brutons Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies[1][2][3][4].
Molecular Weight:
454.48
Purity:
99.71
CAS Number:
[1351636-18-4]
Formula:
C25H22N6O3
Target:
Apoptosis,Btk
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted