CZC-25146 (hydrochloride), CAS [[1330003-04-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: CZC-25146 (hydrochloride), CAS [[1330003-04-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-15800
• Hersteller Artikelnummer: HY-15800
• Alternativnummer: MCE-HY-15800-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CZC-25146 hydrochloride is a potent LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 hydrochloride inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 hydrochloride prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 hydrochloride exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 hydrochloride can increase normal alpha-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 hydrochloride can be used to research Parkinsons disease and liver diseases[1][2][3].

Produkteigenschaften

• Molekulargewicht: 525.00
• CAS Nummer: [1330003-04-7]
• Formel: C22H26ClFN6O4S
• Target-Kategorie: LRRK2,TNK1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound