CZC-25146 (hydrochloride), CAS [[1330003-04-7]] Preis auf Anfrage

Product Overview

• Article Name: CZC-25146 (hydrochloride), CAS [[1330003-04-7]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-15800
• Supplier Catalog Number: HY-15800
• Alternative Catalog Number: MCE-HY-15800-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

CZC-25146 hydrochloride is a potent LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 hydrochloride inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 hydrochloride prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 hydrochloride exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 hydrochloride can increase normal alpha-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 hydrochloride can be used to research Parkinsons disease and liver diseases[1][2][3].

Product Properties

• Molecular Weight: 525.00
• CAS Number: [1330003-04-7]
• Formula: C22H26ClFN6O4S
• Target: LRRK2,TNK1

Application Notes

• Application Notes: MCE Product type: Reference compound