CZC-25146, CAS [[1191911-26-8]]

Produktübersicht

• Artikelname: CZC-25146, CAS [[1191911-26-8]]
• Artikelnummer: MCE-HY-15800A
• Hersteller Artikelnummer: HY-15800A
• Alternativnummer: MCE-HY-15800A-25MG,MCE-HY-15800A-100MG,MCE-HY-15800A-5MG,MCE-HY-15800A-10MMX1ML,MCE-HY-15800A-10MG,MCE-HY-15800A-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

CZC-25146 is a potent and orally active LRRK2 inhibitor with IC50 values of 4.76 nM and 6.87 nM for wild-type LRRK2 and G2019S LRRK2, respectively. CZC-25146 inhibits PLK4, GAK, TNK1, CAMKK2 and PIP4K2C as well. CZC-25146 prevents mutant LRRK2-induced injury of neurons in vitro. CZC-25146 exhibits relatively favorable pharmacokinetic properties in mice. CZC-25146 can increase normal alpha-1-antitrypsin (AAT) secretion and reduce inflammatory cytokines. CZC-25146 can be used to research Parkinsons disease and liver diseases[1][2][3].

Produkteigenschaften

• Molekulargewicht: 488.54
• Reinheit: 99.10
• CAS Nummer: [1191911-26-8]
• Formel: C22H25FN6O4S
• Target-Kategorie: LRRK2,TNK1

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound