(Rac)-Ibrutinib alkyne (Compound 8) is a Btk inhibitor with an IC50 of 0.72 nM. (Rac)-Ibrutinib alkyne can effectively inhibit functions related to the B-cell receptor signaling pathway, with an IC50 of 9 nM for inhibiting Ca flux in Ramos cells. (Rac)-Ibrutinib alkyne can be used in the research of diseases such as rheumatoid arthritis[1].
Molekulargewicht:
438.48
Reinheit:
99.35
CAS Nummer:
[936563-91-6]
Formel:
C25H22N6O2
Target-Kategorie:
Btk,Calcium Channel
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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