(Rac)-Ibrutinib alkyne (Compound 8) is a Btk inhibitor with an IC50 of 0.72 nM. (Rac)-Ibrutinib alkyne can effectively inhibit functions related to the B-cell receptor signaling pathway, with an IC50 of 9 nM for inhibiting Ca flux in Ramos cells. (Rac)-Ibrutinib alkyne can be used in the research of diseases such as rheumatoid arthritis[1].
Molecular Weight:
438.48
Purity:
99.35
CAS Number:
[936563-91-6]
Formula:
C25H22N6O2
Target:
Btk,Calcium Channel
Application Notes:
MCE Product type: Reference compound
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