BMS-986365, CAS [[2446928-30-7]]

Produktübersicht

• Artikelname: BMS-986365, CAS [[2446928-30-7]]
• Artikelnummer: MCE-HY-158101
• Hersteller Artikelnummer: HY-158101
• Alternativnummer: MCE-HY-158101-500MG,MCE-HY-158101-1G,MCE-HY-158101-100MG,MCE-HY-158101-250MG,MCE-HY-158101-25MG,MCE-HY-158101-10MG,MCE-HY-158101-50MG,MCE-HY-158101-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: CC-94676

Produktbeschreibung

BMS-986365 (CC-94676) is an orally active and selective targeted androgen receptor (AR) PROTAC degrader, capable of inducing cereblon (CRBN) E3 ligase-dependent ubiquitination and degradation of the androgen receptor (AR), as well as various AR mutants. BMS-986365 shows significant in vivo potency, degrading AR, inhibiting AR signaling, and restricting tumor growth in animal models of advanced prostate cancer. (Blue: HY-W247437, Black: linker (HY-W126831), Pink: HY-168697)[1][2][3][4][5].

Produkteigenschaften

• Molekulargewicht: 818.91
• Reinheit: 99.92
• CAS Nummer: [2446928-30-7]
• Formel: C41H45F3N8O5S
• Target-Kategorie: Androgen Receptor,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound