VVD-214, CAS [[3026500-20-6]]

Produktübersicht

• Artikelname: VVD-214, CAS [[3026500-20-6]]
• Artikelnummer: MCE-HY-158116
• Hersteller Artikelnummer: HY-158116
• Alternativnummer: MCE-HY-158116-10MMX1ML,MCE-HY-158116-25MG,MCE-HY-158116-5MG,MCE-HY-158116-100MG,MCE-HY-158116-50MG,MCE-HY-158116-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: RO7589831, VVD-133214

Produktbeschreibung

VVD-214 is a synthetic lethal allosteric inhibitor of WRN helicase with an IC50 of 0.1316 µM. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers[1][2].

Produkteigenschaften

• Molekulargewicht: 437.46
• Reinheit: 99.99
• CAS Nummer: [3026500-20-6]
• Formel: C20H21F2N3O4S
• Target-Kategorie: DNA/RNA Synthesis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound