PROTAC TEAD degrader-1, CAS [[3061498-57-2]]

Produktübersicht

• Artikelname: PROTAC TEAD degrader-1, CAS [[3061498-57-2]]
• Artikelnummer: MCE-HY-158342
• Hersteller Artikelnummer: HY-158342
• Alternativnummer: MCE-HY-158342-25MG,MCE-HY-158342-10MG,MCE-HY-158342-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC TEAD degrader-1 (Compound 27) is a PROTAC degrader for transcriptional enhanced associate domain (TEAD). PROTAC TEAD degrader-1 selectively degrades the Flag TEAD2 in a ubiquitin proteasome-dependent manner, with a DC50 of 54.1 nM in 293T cells, inhibits proliferation of NF2-deficient NCI-H226 with an IC50 of 0.21 µM, and regulates expressions of yes associated protein (YAP) target genes. (Pink: TEAD ligand (HY-158400), Black: linker (HY-W008474), Blue: E3 ligase ligand (HY-W087383))[1]

Produkteigenschaften

• Molekulargewicht: 822.83
• Reinheit: 99.82
• CAS Nummer: [3061498-57-2]
• Formel: C44H41F3N6O7
• Target-Kategorie: PROTACs,YAP

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound