RP-2119, CAS [[2922287-81-6]]

Produktübersicht

• Artikelname: RP-2119, CAS [[2922287-81-6]]
• Artikelnummer: MCE-HY-158346
• Hersteller Artikelnummer: HY-158346
• Alternativnummer: MCE-HY-158346-50MG,MCE-HY-158346-25MG,MCE-HY-158346-10MG,MCE-HY-158346-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RP-2119 is an orally bioactive Polymerase Theta (Poltheta) inhibitor, with an IC50 of 0.7 nM against human Poltheta ATPase. RP-2119 reduces Poltheta activity and exerts antiproliferative effects in BRCA2-deficient cancer cells. RP-2119 exhibits antitumor activity in BRCA2-deficient cancer cell xenograft mouse models. RP-2119 can be used for the research of cancer and homologous recombination-deficient cancers, including brca1/brca2-mutant cancers and shld2-mutant cancers[1][2].

Produkteigenschaften

• Molekulargewicht: 507.52
• Reinheit: 99.94
• CAS Nummer: [2922287-81-6]
• Formel: C24H19F2N7O2S
• Target-Kategorie: DNA/RNA Synthesis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound