2-APQC, CAS [[500271-63-6]]

Produktübersicht

• Artikelname: 2-APQC, CAS [[500271-63-6]]
• Artikelnummer: MCE-HY-158426
• Hersteller Artikelnummer: HY-158426
• Alternativnummer: MCE-HY-158426-1G,MCE-HY-158426-100MG,MCE-HY-158426-250MG,MCE-HY-158426-10MG,MCE-HY-158426-10MMX1ML,MCE-HY-158426-500MG,MCE-HY-158426-25MG,MCE-HY-158426-50MG,MCE-HY-158426-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

2-APQC is an orally active and selective agonist of Sirtuin-3 (SIRT3) (Kd=2.756 µM), antagonizes Isoproterenol/ISO (HY-B0468)-induced cytotoxicity. 2-APQC activates the SIRT3-PYCR1 axis to enhance mitochondrial proline metabolism and inhibit the ROS-p38MAPK pathway by inhibiting signaling pathways such as mTOR-p70S6K, JNK, and TGF-beta/Smad3. 2-APQC also activates the AMPK-Parkin axis to alleviate myocardial hypertrophy and fibrosis and protect cardiac function. 2-APQC can be used in the study of heart failure[1].

Produkteigenschaften

• Molekulargewicht: 405.47
• Reinheit: 99.70
• CAS Nummer: [500271-63-6]
• Formel: C23H24FN5O
• Target-Kategorie: Sirtuin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound