GT-653

Produktübersicht

• Artikelname: GT-653
• Artikelnummer: MCE-HY-158432
• Hersteller Artikelnummer: HY-158432
• Alternativnummer: MCE-HY-158432-100MG,MCE-HY-158432-1MG,MCE-HY-158432-5MG,MCE-HY-158432-50MG,MCE-HY-158432-10MG,MCE-HY-158432-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GT-653 is a PROTAC degrader for lysine-specific demethylase 5B (KDM5B). GT-653 degrades 68.35% KDM5B at 10 µM in a ubiquitin proteasome-dependent manner, upregulates H3K4me3 levels, and activates the type-I interferon signaling pathway in prostate cancer cells 22RV1. (Pink: KDM5B ligand (HY-158433), Black: Linker (HY-W004896), Blue: E3 ligase ligand (HY-103596))[1]

Produkteigenschaften

• Molekulargewicht: 653.60
• Reinheit: 99.84
• Formel: C32H27N7O9
• Target-Kategorie: Histone Demethylase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound