SACLAC, CAS [[2248703-42-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: SACLAC, CAS [[2248703-42-4]] Preis auf Anfrage
• Artikelnummer: MCE-HY-158783
• Hersteller Artikelnummer: HY-158783
• Alternativnummer: MCE-HY-158783-10MG,MCE-HY-158783-50MG,MCE-HY-158783-5MG,MCE-HY-158783-25MG,MCE-HY-158783-100MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SACLAC, a Ceramide analog, is a potent and covalent acid ceramidase (ASAH1, AC) inhibitor with a Ki of 97.1 nM. SACLAC effectively blocks AC activity and induces a decrease in sphingosine 1-phosphate (S1P) and total ceramide levels. SACLAC reduces the levels of splicing factor SF3B1 and alternative Mcl-1 mRNA splicing, increases pro-apoptotic Mcl-1S levels to induce apoptosis in acute myeloid leukemia (AML) cells. SACLAC reduces the leukemic burden in human AML xenograft mouse models[1][2].

Produkteigenschaften

• Molekulargewicht: 377.99
• Reinheit: 99.70
• CAS Nummer: [2248703-42-4]
• Formel: C20H40ClNO3
• Target-Kategorie: Apoptosis,Bcl-2 Family,Ceramidase,LPL Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound