AD1058 is an orally active, selective, and BBB-permeable inhibitor of ATR (IC50: 1.6 nM). AD1058 exhibits anticancer activity by inhibiting tumor cell proliferation, inducing cell cycle arrest, and promoting apoptosis. AD1058 is suitable for research on advanced malignancies and brain metastases[1].
Molekulargewicht:
412.47
Reinheit:
98.11
CAS Nummer:
[2907782-78-7]
Formel:
C19H20N6O3S
Target-Kategorie:
AMPK,Apoptosis,ATM/ATR,mTOR,Src
Anwendungsbeschreibung:
Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten