AD1058 is an orally active, selective, and BBB-permeable inhibitor of ATR (IC50: 1.6 nM). AD1058 exhibits anticancer activity by inhibiting tumor cell proliferation, inducing cell cycle arrest, and promoting apoptosis. AD1058 is suitable for research on advanced malignancies and brain metastases[1].
Molecular Weight:
412.47
Purity:
98.11
CAS Number:
[2907782-78-7]
Formula:
C19H20N6O3S
Target:
AMPK,Apoptosis,ATM/ATR,mTOR,Src
Application Notes:
Reference compound
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