MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line)[1].
Molekulargewicht:
596.60
Reinheit:
98.34
CAS Nummer:
[328540-44-9]
Formel:
C18H8Br2ClF3N4O2S
Target-Kategorie:
IFNAR,Tim3,TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten