MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line)[1].
Molecular Weight:
596.60
Purity:
98.34
CAS Number:
[328540-44-9]
Formula:
C18H8Br2ClF3N4O2S
Target:
IFNAR,Tim3,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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