PD-1/PD-L1-IN-54, CAS [[1393644-68-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: PD-1/PD-L1-IN-54, CAS [[1393644-68-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-159892
• Hersteller Artikelnummer: HY-159892
• Alternativnummer: MCE-HY-159892-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PD-1/PD-L1-IN-54 (Compound 6) is a moderately affinic PD-1/PD-L1 inhibitor (KD: PD-1, 55.8 µM, PD-L1, 46.4 µM, IC50: 88.6 µM). PD-1/PD-L1-IN-54 inhibits PD-1/PD-L1 interactions and shows anticancer activity by activating CD8+ T cells, upregulating PD-1 expression, and increasing secretion of IFN-gamma and IL-2. PD-1/PD-L1-IN-54 inhibits cancer cell proliferation and promotes apoptosis. PD-1/PD-L1-IN-54 also regulates T cell immunity through the PI3K/Akt pathway correlated with PD-1/PD-L1[1].

Produkteigenschaften

• Molekulargewicht: 368.77
• CAS Nummer: [1393644-68-2]
• Formel: C17H17ClO7
• Target-Kategorie: Akt,IFNAR,Interleukin Related,PD-1/PD-L1,PI3K

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound