PD-1/PD-L1-IN-54, CAS [[1393644-68-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-159892
Supplier Catalog Number:
HY-159892
Alternative Catalog Number:
MCE-HY-159892-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PD-1/PD-L1-IN-54 (Compound 6) is a moderately affinic PD-1/PD-L1 inhibitor (KD: PD-1, 55.8 µM, PD-L1, 46.4 µM, IC50: 88.6 µM). PD-1/PD-L1-IN-54 inhibits PD-1/PD-L1 interactions and shows anticancer activity by activating CD8+ T cells, upregulating PD-1 expression, and increasing secretion of IFN-gamma and IL-2. PD-1/PD-L1-IN-54 inhibits cancer cell proliferation and promotes apoptosis. PD-1/PD-L1-IN-54 also regulates T cell immunity through the PI3K/Akt pathway correlated with PD-1/PD-L1[1].
Molecular Weight:
368.77
CAS Number:
[1393644-68-2]
Formula:
C17H17ClO7
Target:
Akt,IFNAR,Interleukin Related,PD-1/PD-L1,PI3K
Application Notes:
MCE Product type: Reference compound
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