Tubulin Polymerization-IN-1 prodrug, CAS [[3033099-32-7]] Preis auf Anfrage

Produktübersicht

• Artikelname: Tubulin Polymerization-IN-1 prodrug, CAS [[3033099-32-7]] Preis auf Anfrage
• Artikelnummer: MCE-HY-159921
• Hersteller Artikelnummer: HY-159921
• Alternativnummer: MCE-HY-159921-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a palladium (Pd)-mediated tubulin polymerization inhibitor prodrug. Developed based on colchicine binding site inhibitors (CBSIs), it reduces toxicity and enhances targeted release properties. Compared to the parent compound, Tubulin Polymerization-IN-1 prodrug exhibited 68.3-fold lower cytotoxicity, which can be restored in situ in the presence of Pd resin. Mechanistic studies showed that its anticancer activity is consistent with CBSIs. In vivo, Tubulin Polymerization-IN-1 prodrug significantly inhibited tumor growth (63.2%) when activated by Pd resin. It holds promise for research in the field of anticancer therapy[1].

Produkteigenschaften

• Molekulargewicht: 398.43
• CAS Nummer: [3033099-32-7]
• Formel: C22H23FN2O4
• Target-Kategorie: Microtubule/Tubulin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound