UBX-382, CAS [[2884554-45-2]]

Produktübersicht

• Artikelname: UBX-382, CAS [[2884554-45-2]]
• Artikelnummer: MCE-HY-160142
• Hersteller Artikelnummer: HY-160142
• Alternativnummer: MCE-HY-160142-25MG,MCE-HY-160142-10MG,MCE-HY-160142-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

UBX-382 is an orally active BTK PROTAC degrader with a DC50 of 4.56 nM. UBX-382 inhibits B-cell receptor signaling by targeting BTK. UBX-382 shows superior degradation activity for wild-type and mutant BTK proteins. UBX-382 inhibits tumor growth in murine xenograft models harboring wild-type or C481S mutant BTK-expressing TMD-8 cells. UBX-382 can be used for the study of B-cell-related blood cancers[1].

Produkteigenschaften

• Molekulargewicht: 752.86
• Reinheit: 96.20
• CAS Nummer: [2884554-45-2]
• Formel: C42H44N10O4
• Target-Kategorie: Btk,ERK,MEK,PROTACs,Syk

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound