UBX-382, CAS [[2884554-45-2]]

Product Overview

• Article Name: UBX-382, CAS [[2884554-45-2]]
• Biozol Catalog Number: MCE-HY-160142
• Supplier Catalog Number: HY-160142
• Alternative Catalog Number: MCE-HY-160142-25MG,MCE-HY-160142-10MG,MCE-HY-160142-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

UBX-382 is an orally active BTK PROTAC degrader with a DC50 of 4.56 nM. UBX-382 inhibits B-cell receptor signaling by targeting BTK. UBX-382 shows superior degradation activity for wild-type and mutant BTK proteins. UBX-382 inhibits tumor growth in murine xenograft models harboring wild-type or C481S mutant BTK-expressing TMD-8 cells. UBX-382 can be used for the study of B-cell-related blood cancers[1].

Product Properties

• Molecular Weight: 752.86
• Purity: 96.20
• CAS Number: [2884554-45-2]
• Formula: C42H44N10O4
• Target: Btk,ERK,MEK,PROTACs,Syk

Application Notes

• Application Notes: Reference compound