Birelentinib, CAS [[2662512-15-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Birelentinib, CAS [[2662512-15-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-160167
• Hersteller Artikelnummer: HY-160167
• Alternativnummer: MCE-HY-160167-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: DZD8586

Produktbeschreibung

Birelentinib (DZD8586) is an orally effective, selective, non-covalent inhibitor targeting LYN tyrosine kinase and BTK tyrosine kinase, capable of penetrating the blood-brain barrier. Birelentinib exhibits concentration-dependent antiproliferative effects in RI-1 cells and diffuse large B-cell lymphoma (DLBCL) cell lines carrying BTK resistance mutations (such as C481X, V416L, etc.). Birelentinib blocks both BTK-dependent and independent signaling of the B-cell receptor (BCR), thereby inhibiting tumor cell proliferation and inducing cell death. Birelentinib can be used in research to overcome resistance to existing covalent and non-covalent BTK inhibitors in B-cell non-Hodgkin lymphoma (B-NHL)[1][2].

Produkteigenschaften

• Molekulargewicht: 453.44
• CAS Nummer: [2662512-15-2]
• Formel: C23H21F2N5O3
• Target-Kategorie: Btk,Src

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound