Birelentinib, CAS [[2662512-15-2]] Preis auf Anfrage

Product Overview

• Article Name: Birelentinib, CAS [[2662512-15-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-160167
• Supplier Catalog Number: HY-160167
• Alternative Catalog Number: MCE-HY-160167-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: DZD8586

Product Description

Birelentinib (DZD8586) is an orally effective, selective, non-covalent inhibitor targeting LYN tyrosine kinase and BTK tyrosine kinase, capable of penetrating the blood-brain barrier. Birelentinib exhibits concentration-dependent antiproliferative effects in RI-1 cells and diffuse large B-cell lymphoma (DLBCL) cell lines carrying BTK resistance mutations (such as C481X, V416L, etc.). Birelentinib blocks both BTK-dependent and independent signaling of the B-cell receptor (BCR), thereby inhibiting tumor cell proliferation and inducing cell death. Birelentinib can be used in research to overcome resistance to existing covalent and non-covalent BTK inhibitors in B-cell non-Hodgkin lymphoma (B-NHL)[1][2].

Product Properties

• Molecular Weight: 453.44
• CAS Number: [2662512-15-2]
• Formula: C23H21F2N5O3
• Target: Btk,Src

Application Notes

• Application Notes: MCE Product type: Reference compound