HA-9104, CAS [[2412367-83-8]]

Produktübersicht

• Artikelname: HA-9104, CAS [[2412367-83-8]]
• Artikelnummer: MCE-HY-160799
• Hersteller Artikelnummer: HY-160799
• Alternativnummer: MCE-HY-160799-5MG,MCE-HY-160799-10MG,MCE-HY-160799-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HA-9104 is a potent and selective cullin-5 neddylation inhibitor with an IC50 of 33.29 µM. HA-9104 induces apoptosis by reducing the polyubiquitination modification of NOXA, prolonging the half-life of NOXA and causing its accumulation. HA-9104 forms DNA adducts, induces DNA damage, triggers replication stress and ROS production, and leads to G2/M cell cycle arrest. HA-9104 exhibits radiosensitizing effects. HA-9104 can be used in research related to lung cancer and pancreatic cancer[1][2].

Produkteigenschaften

• Molekulargewicht: 465.55
• Reinheit: 98.54
• CAS Nummer: [2412367-83-8]
• Formel: C28H27N5O2
• Target-Kategorie: Apoptosis,DNA/RNA Synthesis,E1/E2/E3 Enzyme,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1