Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a Ki of 0.6 nM for 5-HT4 receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models[1].
Molekulargewicht:
456.92
Reinheit:
98.66
CAS Nummer:
[769901-96-4]
Formel:
C23H25ClN4O4
Target-Kategorie:
5-HT Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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