Bethanidine (sulfate), CAS [[114-85-2]] Preis auf Anfrage
Artikelnummer:
MCE-HY-16094
Hersteller Artikelnummer:
HY-16094
Alternativnummer:
MCE-HY-16094-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
BW 467C60
Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neurone blockers with sympathomimetic effects similar to bretylium and guanethidine in various animal models, particularly in cats. They inhibit the release of noradrenaline during nerve stimulation and enhance smooth muscle responses to adrenaline and noradrenaline. Bethanidine sulfate increases pressor responses to tyramine, though this effect diminishes with higher doses. Unlike guanethidine, Bethanidine sulfate does not deplete pressor amine content in the iris of cats post-administration. It also briefly inhibits autonomic cholinergic mechanisms and causes temporary neuromuscular paralysis in large doses, contrasting with its prolonged adrenergic neurone blocking effects[1].
Molekulargewicht:
275.32
CAS Nummer:
[114-85-2]
Formel:
C10H17N3O4S
Target-Kategorie:
Adrenergic Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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