Bethanidine (sulfate), CAS [[114-85-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-16094
Supplier Catalog Number:
HY-16094
Alternative Catalog Number:
MCE-HY-16094-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
BW 467C60
Bethanidine sulfate and its ortho-chloro derivative (BW 392C60) are potent adrenergic neurone blockers with sympathomimetic effects similar to bretylium and guanethidine in various animal models, particularly in cats. They inhibit the release of noradrenaline during nerve stimulation and enhance smooth muscle responses to adrenaline and noradrenaline. Bethanidine sulfate increases pressor responses to tyramine, though this effect diminishes with higher doses. Unlike guanethidine, Bethanidine sulfate does not deplete pressor amine content in the iris of cats post-administration. It also briefly inhibits autonomic cholinergic mechanisms and causes temporary neuromuscular paralysis in large doses, contrasting with its prolonged adrenergic neurone blocking effects[1].
Molecular Weight:
275.32
CAS Number:
[114-85-2]
Formula:
C10H17N3O4S
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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