APP degrader-1 (Compound 0152) is an orally active amyloid precursor protein (APP) degrader that induces APP degradation and reduces the extracellular release of Abeta42. APP degrader-1 can bind to both CAPRIN1 and APP, and enhances their interaction as well as CAPRIN1-mediated APP degradation through the endosome-lysosome pathway[1].
Molekulargewicht:
412.46
Reinheit:
98.35
CAS Nummer:
[3090769-17-5]
Formel:
C20H20N4O4S
Target-Kategorie:
Amyloid-beta
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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