APP degrader-1 (Compound 0152) is an orally active amyloid precursor protein (APP) degrader that induces APP degradation and reduces the extracellular release of Abeta42. APP degrader-1 can bind to both CAPRIN1 and APP, and enhances their interaction as well as CAPRIN1-mediated APP degradation through the endosome-lysosome pathway[1].
Molecular Weight:
412.46
Purity:
98.35
CAS Number:
[3090769-17-5]
Formula:
C20H20N4O4S
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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