DNA relaxation-IN-1 (Compound 27) is a DNA ligase 1 DNA Lig1) inhibitor. DNA relaxation-IN-1 inhibits DNA ligation and disrupts the DNA relaxing activity of DNA Lig1. DNA relaxation-IN-1 induces Apoptosis. DNA relaxation-IN-1, in combination with Topotecan (HY-13768), exhibits synergistic antiproliferative effects against colorectal cancer[1].
Molekulargewicht:
493.62
Reinheit:
99.37
CAS Nummer:
[2190506-29-5]
Formel:
C30H27N3O2S
Target-Kategorie:
Apoptosis,DNA/RNA Synthesis
Anwendungsbeschreibung:
MCE Product type: Reference compound
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