Cilengitide, CAS [[188968-51-6]]

Produktübersicht

• Artikelname: Cilengitide, CAS [[188968-51-6]]
• Artikelnummer: MCE-HY-16141
• Hersteller Artikelnummer: HY-16141
• Alternativnummer: MCE-HY-16141-1G,MCE-HY-16141-10MMX1ML,MCE-HY-16141-50MG,MCE-HY-16141-100MG,MCE-HY-16141-5MG,MCE-HY-16141-10MG,MCE-HY-16141-25MG,MCE-HY-16141-200MG,MCE-HY-16141-500MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: EMD 121974

Produktbeschreibung

Cilengitide (EMD 121974) is a potent integrins antagonist with IC50s of 0.61 nM (alphanybeta3), 8.4 nM (alphanybeta5) and 14.9 nM (alpha5beta1), respectively. Cilengitide inhibits the binding of alphanybeta3 and alphanybeta5 to Vitronectin with IC50s of 4 nM and 79 nM, respectively. Cilengitide inhibits TGF-beta/Smad signaling, mediates PD-L1 expression. Cilengitide also induces apoptosis, shows antiangiogenic effect in the research against glioblastoma and other cancers[1][2][3].

Produkteigenschaften

• Molekulargewicht: 588.66
• Reinheit: 99.80
• CAS Nummer: [188968-51-6]
• Formel: C27H40N8O7
• Target-Kategorie: Apoptosis,Autophagy,Integrin,PD-1/PD-L1,STAT

Anwendungsbeschreibung

• Anwendungsbeschreibung: Reference compound