PROTAC EGFR degrader 9, CAS [[2992670-33-2]]

Produktübersicht

• Artikelname: PROTAC EGFR degrader 9, CAS [[2992670-33-2]]
• Artikelnummer: MCE-HY-161536
• Hersteller Artikelnummer: HY-161536
• Alternativnummer: MCE-HY-161536-100MG,MCE-HY-161536-50MG,MCE-HY-161536-5MG,MCE-HY-161536-25MG,MCE-HY-161536-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC EGFR degrader 9 (Compound C6) is an orally active CRBN-based PROTAC EGFR degrader. PROTAC EGFR degrader 9 exhibits a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFRL858R/T790M/C797S. PROTAC EGFR degrader 9 exhibits potent degradation activity against various EGFR mutants, while sparing the EGFRWT. (Blue: CRBN ligand (HY-A0003), Black: linker (HY-161613), Pink: EGFR inhibitor (HY-161537))[1].

Produkteigenschaften

• Molekulargewicht: 899.98
• Reinheit: 98.35
• CAS Nummer: [2992670-33-2]
• Formel: C45H48F3N9O6S
• Target-Kategorie: Apoptosis,EGFR,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound