PROTAC ATR degrader-2, CAS [[3010273-12-5]]

Produktübersicht

• Artikelname: PROTAC ATR degrader-2, CAS [[3010273-12-5]]
• Artikelnummer: MCE-HY-161615
• Hersteller Artikelnummer: HY-161615
• Alternativnummer: MCE-HY-161615-25MG,MCE-HY-161615-5MG,MCE-HY-161615-50MG,MCE-HY-161615-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PROTAC ATR degrader-2 (Compound 8i) is a PROTAC degrader for ATR, through of . PROTAC ATR degrader-2 degrades ATR in acute myeloid leukemia (AML) cells MV-4-11 and MOLM-13, with DC50 of 22.9 and 34.5 nM. APROTAC ATR degrader-2 induces apoptosis, inhibits proliferations of AML cells. PROTAC ATR degrader-2 exhibits good pharmacokinetics charachers and antitumor efficacy against AML in mouse model. (Pink: ATR ligand (HY-161616), Blue:E3 ligase ligand Lenalidomide (HY-A0003), Black: linker)[1]

Produkteigenschaften

• Molekulargewicht: 743.81
• Reinheit: 99.73
• CAS Nummer: [3010273-12-5]
• Formel: C40H41N9O6
• Target-Kategorie: Apoptosis,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound