PROTAC ATR degrader-2, CAS [[3010273-12-5]]

Product Overview

• Article Name: PROTAC ATR degrader-2, CAS [[3010273-12-5]]
• Biozol Catalog Number: MCE-HY-161615
• Supplier Catalog Number: HY-161615
• Alternative Catalog Number: MCE-HY-161615-25MG,MCE-HY-161615-5MG,MCE-HY-161615-50MG,MCE-HY-161615-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC ATR degrader-2 (Compound 8i) is a PROTAC degrader for ATR, through of . PROTAC ATR degrader-2 degrades ATR in acute myeloid leukemia (AML) cells MV-4-11 and MOLM-13, with DC50 of 22.9 and 34.5 nM. APROTAC ATR degrader-2 induces apoptosis, inhibits proliferations of AML cells. PROTAC ATR degrader-2 exhibits good pharmacokinetics charachers and antitumor efficacy against AML in mouse model. (Pink: ATR ligand (HY-161616), Blue:E3 ligase ligand Lenalidomide (HY-A0003), Black: linker)[1]

Product Properties

• Molecular Weight: 743.81
• Purity: 99.73
• CAS Number: [3010273-12-5]
• Formula: C40H41N9O6
• Target: Apoptosis,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound