PLX-3618, CAS [[2851986-76-8]]

Produktübersicht

• Artikelname: PLX-3618, CAS [[2851986-76-8]]
• Artikelnummer: MCE-HY-161779
• Hersteller Artikelnummer: HY-161779
• Alternativnummer: MCE-HY-161779-10MMX1ML,MCE-HY-161779-50MG,MCE-HY-161779-5MG,MCE-HY-161779-10MG,MCE-HY-161779-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

PLX-3618 is a selective BRD4 molecular glue degrader with a DC50 of 12.2 nM. PLX-3618 promotes the polyubiquitination and subsequent proteasomal degradation of BRD4 by recruiting the E3 ligase substrate receptor DCAF11. PLX-3618 inhibits the proliferation of various cancer cells and induces apoptosis in acute myeloid leukemia (AML) cells. PLX-3618 can be used in studies related to acute myeloid leukemia (AML)[1].

Produkteigenschaften

• Molekulargewicht: 601.68
• Reinheit: 99.86
• CAS Nummer: [2851986-76-8]
• Formel: C32H27N9O2S
• Target-Kategorie: Apoptosis,Epigenetic Reader Domain,Molecular Glues

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1