PLX-3618, CAS [[2851986-76-8]]

Product Overview

• Article Name: PLX-3618, CAS [[2851986-76-8]]
• Biozol Catalog Number: MCE-HY-161779
• Supplier Catalog Number: HY-161779
• Alternative Catalog Number: MCE-HY-161779-10MMX1ML,MCE-HY-161779-50MG,MCE-HY-161779-5MG,MCE-HY-161779-10MG,MCE-HY-161779-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PLX-3618 is a selective BRD4 molecular glue degrader with a DC50 of 12.2 nM. PLX-3618 promotes the polyubiquitination and subsequent proteasomal degradation of BRD4 by recruiting the E3 ligase substrate receptor DCAF11. PLX-3618 inhibits the proliferation of various cancer cells and induces apoptosis in acute myeloid leukemia (AML) cells. PLX-3618 can be used in studies related to acute myeloid leukemia (AML)[1].

Product Properties

• Molecular Weight: 601.68
• Purity: 99.86
• CAS Number: [2851986-76-8]
• Formula: C32H27N9O2S
• Target: Apoptosis,Epigenetic Reader Domain,Molecular Glues

Application Notes

• Application Notes: MCE Product type: Reference compound1