HVH-2930, CAS [[3034605-72-3]]

Produktübersicht

• Artikelname: HVH-2930, CAS [[3034605-72-3]]
• Artikelnummer: MCE-HY-161781
• Hersteller Artikelnummer: HY-161781
• Alternativnummer: MCE-HY-161781-50MG,MCE-HY-161781-10MG,MCE-HY-161781-5MG,MCE-HY-161781-100MG,MCE-HY-161781-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HVH-2930 is an inhibitor for heat shock protein 90 (HSP90). HVH-2930 inhibits cell viability of BT474 (Trastuzumab (HY-P9907) sensitive) and JIMT-1 (Trastuzumab (HY-P9907) resistant), with IC50 of 6.86 µM and 4.42 µM, through downregulation of HSP90 clients HER2, p-HER2, AKT, p-AKT, cyclin D1 and survivin. HVH-2930 exhibits antitumor efficacy in mouse models. HVH-2930 exhibits good pharmacokinetic characteristics in mice[1].

Produkteigenschaften

• Molekulargewicht: 488.62
• Reinheit: 96.54
• CAS Nummer: [3034605-72-3]
• Formel: C29H36N4O3
• Target-Kategorie: Akt,EGFR,HSP,Survivin

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1