HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-161783
• Hersteller Artikelnummer: HY-161783
• Alternativnummer: MCE-HY-161783-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

HDAC6-IN-45 (Compound 15) is a selective inhibitor for HDAC6 with IC50 of 15.2 nM. HDAC6-IN-45 exhibits neurotrophic through the upregulation of GAP43 and Beta-3 tubulin markers. HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, inhibits apoptosis in PC12, and exhibits neuroprotective efficacy in SCOP-induced zebrafish Alzheimers Disease models. HDAC6-IN-45 exhibits antioxidant activity and good blood-brain barrier (BBB) permeability[1].

Produkteigenschaften

• Molekulargewicht: 393.45
• CAS Nummer: [3048532-05-1]
• Formel: C23H24FN3O2
• Target-Kategorie: Apoptosis,HDAC,Keap1-Nrf2,Reactive Oxygen Species (ROS)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1