HDAC6-IN-45, CAS [[3048532-05-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-161783
Supplier Catalog Number:
HY-161783
Alternative Catalog Number:
MCE-HY-161783-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HDAC6-IN-45 (Compound 15) is a selective inhibitor for HDAC6 with IC50 of 15.2 nM. HDAC6-IN-45 exhibits neurotrophic through the upregulation of GAP43 and Beta-3 tubulin markers. HDAC6-IN-45 activates the Nrf2 signaling pathway, reduces H2O2-induced ROS production, inhibits apoptosis in PC12, and exhibits neuroprotective efficacy in SCOP-induced zebrafish Alzheimers Disease models. HDAC6-IN-45 exhibits antioxidant activity and good blood-brain barrier (BBB) permeability[1].
Molecular Weight:
393.45
CAS Number:
[3048532-05-1]
Formula:
C23H24FN3O2
Target:
Apoptosis,HDAC,Keap1-Nrf2,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
