DNDI-6174, CAS [[2868298-43-3]]

Artikelnummer: MCE-HY-162066
Artikelname: DNDI-6174, CAS [[2868298-43-3]]
Artikelnummer: MCE-HY-162066
Hersteller Artikelnummer: HY-162066
Alternativnummer: MCE-HY-162066-25MG,MCE-HY-162066-50MG,MCE-HY-162066-10MG,MCE-HY-162066-10MMX1ML,MCE-HY-162066-1MG,MCE-HY-162066-5MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
DNDI-6174 is an orally active Leishmania cytochrome b (Qi site of cytochrome bc1 complex/complex III) inhibitor. DNDI-6174 binds to the Qi site of Leishmania cytochrome b, inhibits cytochrome bc1 complex activity in the parasites electron transport chain across promastigote and axenic amastigote stages. DNDI-6174 reduces parasite burden in rodent models, inhibits growth of various Leishmania species, drug-resistant clinical isolates, and Trypanosoma cruzi, with marginal activity against Trypanosoma brucei. DNDI-6174 can be used for the research of visceral leishmaniasis, cutaneous leishmaniasis[1].
Molekulargewicht: 307.31
Reinheit: 97.28
CAS Nummer: [2868298-43-3]
Formel: C16H13N5O2
Target-Kategorie: Parasite
Anwendungsbeschreibung: MCE Product type: Reference compound