DNDI-6174, CAS [[2868298-43-3]]

Product Overview

• Article Name: DNDI-6174, CAS [[2868298-43-3]]
• Biozol Catalog Number: MCE-HY-162066
• Supplier Catalog Number: HY-162066
• Alternative Catalog Number: MCE-HY-162066-25MG,MCE-HY-162066-50MG,MCE-HY-162066-10MG,MCE-HY-162066-10MMX1ML,MCE-HY-162066-1MG,MCE-HY-162066-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

DNDI-6174 is an orally active Leishmania cytochrome b (Qi site of cytochrome bc1 complex/complex III) inhibitor. DNDI-6174 binds to the Qi site of Leishmania cytochrome b, inhibits cytochrome bc1 complex activity in the parasites electron transport chain across promastigote and axenic amastigote stages. DNDI-6174 reduces parasite burden in rodent models, inhibits growth of various Leishmania species, drug-resistant clinical isolates, and Trypanosoma cruzi, with marginal activity against Trypanosoma brucei. DNDI-6174 can be used for the research of visceral leishmaniasis, cutaneous leishmaniasis[1].

Product Properties

• Molecular Weight: 307.31
• Purity: 97.28
• CAS Number: [2868298-43-3]
• Formula: C16H13N5O2
• Target: Parasite

Application Notes

• Application Notes: MCE Product type: Reference compound