MS8847, CAS [[3050872-59-5]]

Produktübersicht

• Artikelname: MS8847, CAS [[3050872-59-5]]
• Artikelnummer: MCE-HY-162250
• Hersteller Artikelnummer: HY-162250
• Alternativnummer: MCE-HY-162250-25MG,MCE-HY-162250-1MG,MCE-HY-162250-5MG,MCE-HY-162250-10MG,MCE-HY-162250-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

MS8847 is a PROTAC degrader and antiproliferative agent targeting EZH2 (DC50=34.4 nM in EOL-1 MLL-rAML cells). MS8847 recruits the E3 ligase von Hippel-Lindau (VHL) to mediate the degradation of EZH2 via the ubiquitin-proteasome system. MS8847 induces antiproliferative effects in MLL-rearranged acute myeloid leukemia cells and inhibits the growth of triple-negative breast cancer cell lines or 3D triple-negative breast cancer models. MS8847 is applicable to research related to MLL-rearranged acute myeloid leukemia and triple-negative breast cancer[1].

Produkteigenschaften

• Molekulargewicht: 1239.65
• Reinheit: 99.78
• CAS Nummer: [3050872-59-5]
• Formel: C70H98N10O8S
• Target-Kategorie: Histone Methyltransferase,PROTACs

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound